Therapeutic option for patients with TN CLL

Factsheet describing the effectiveness and safety of a BTKi treatment in patients with treatment naïve chronic lymphocytic leukemia (TN CLL).

SEQUOIA is a global phase 3, open label study of zanubrutinib in patients with previously untreated chronic lymphocytic leukemia (CLL), including patients without del(17p) [cohort 1]
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Participants in cohort 1 were randomized 1:1 to either zanubrutinib (arm A) or bendamustine plus rituximab (B+R) (arm B). The safety and efficacy analyses after a median follow-up time
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Participants in cohort 3 received treatment with zanubrutinib and venetoclax and early results from these patients with del(17p) and/or TP53,,h 6uP MZD!DDwDW V+5+.



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